Be Young and Healthy from the Inside Out

Inner-Age™, a revolution in biological age measurement™
At last, a comprehensive, science based system exists that can prove how successfully you are aging! Inner-Age™ is a clinical based system that utilizes physical tests, blood and urine to capture, record and measure 150 biochemical markers.

Inner-Age™ highlights your good and bad aging regions. Acting upon this, lifestyle and supplements etc., can be adjusted positively. Inner-Age™ is the ultimate early-warning disorder indicator, allowing you to make individual and precise changes, so that hopefully the issue never becomes a problem.
Inner-Age™ enables you to be able to compare your age/health status to your "chronological" age-group, and see how well you are doing.
Inner-Age™ can help to substantiate if your anti-aging/ supplement/ lifestyle regime is working for you, and if it isn't, where you should then be focusing changes so that it does!
Inner-Age™ records a vast array of biological age markers quickly and easily, and therefore it enables you to stay on the cutting-edge of health technology and react promptly to the latest published medical information.
Inner-Age™ keeps you ahead of the "crowd." The Inner-Age™ unique and patented visualizations show you for the first time a true holistic picture of your aging and health.
Now you can see your Inner-Age™.

Introduction to the Inner-Age™ System
Inner-Age is a software system that operates via a computer in your clinic, that is connected via a secure and encrypted internet connection to a central international database.

The software records all of the patient's data, including biomarkers and general health information, then Inner-Age calculates the biological age and the Aging-Rate™.

These results are displayed in the form of simple, but unique visual pictures, that provide a clear and powerful summary of the current physical state of the patient, and the priority areas of attention.

Furthermore, information about anti-aging medicine protocols and products is also provided.

All of the information gathered on the system is compared to published clinical data, thus providing the scientific backing that is often lacking in preventative medicine.

Inner-Age allows for a vast amount of information about the patient's biomarkers to be recorded, evaluated and assessed, and thereby helps to reveal the unseen future health trends, normally invisible from the standard perspective.

Finally, Inner-Age provides a clear, comprehensive and scientific solution to measure biological age, and to establish the proof behind anti-aging/ preventative medicine.

For more information please contact HB Health

The Inner-Age™ Concept
This area is about the science behind Inner-Age.

Over the course of nearly 3-years, the Inner-Age team and scientific panel have looked at approximately 2000 published clinical studies, of 500,000 patient data..

In the end, the Inner-Age medical panel identified three categories which are described below.

Biomarkers
From more than 2000 published clinical studies, the Inner-Age medical panel identified 24 full biomarkers.

Full biomarkers are classified as markers that:

Can be used to determine the biological age of a patient.
Are the results of human clinical assessment.
Are based on a significant representative sample.
Result in a clear association with aging.
Result in a relatively narrow standard deviation.
Are supported by multiple complementary research studies.
Are available across the chronological ages of 25 to 80.
The biomarkers captured, recorded and assessed by the current Inner-Age System are as follows: (Unless marked, biomarkers are for male and female):

17-ketosteroid/ 17-hydroxycortiosteroid ratio (male)
Ascorbic acid
Basal Metabolic Rate
Blood pressure- pulse
Blood pressure- systolic
Body Mass Index (female)
Caries index
Creatinine clearance
DHEA-S
Fibrinogen
Hair baldness (male)
Hair grayness
Handgrip strength- strongest hand
Hemoglobin A1C
Lung capacity- FEV1
Lung capacity- FVC
Maximum oxygen update (male)
Near vision
Noradrenaline- plasma (male)
Peridontal index
PSA total (male)
Skin elasticity
Testosterone free (male)
Zinc- serum

Candidate Biomarkers
From more than 2000 published clinical studies, the Inner-Age medical panel identified 41 candidate biomarkers.

Candidate biomarkers are classified as markers that:

Are the results of human clinical assessment.
Result in a clear association with aging.
But their sample size may not be representative enough, for example, the data available may only be for Japanese men, or industrial workers, or athletes etc.
Perhaps no standard deviation information is provided.
There is incomplete data to complete the required chronological ages of 25 to 80.
There may be other statistical challenges.
It is envisaged that many of these candidate biomarkers will become full biomarkers once enough further data has been captured. The advantage of the Inner-Age System is that it provides for the global capture of data, and that once approved as a biomarker, the candidate biomarker can be quickly updated.

The candidate biomarkers captured and recorded by the current Inner-Age System are as follows: (Unless marked candidate bio-makers are for male and female):

17-ketosteroid/17-hydroxycorticosteroid ratio (female)
Albumin
Androstenedione
Apolipoprotein B
Arcus Senilis
BGP
Body flexibility
BMI- Body Mass Index (male)
BUN (Blood Urea Nitrogen)
Cholesterol LDL
Cholesterol total
Copper (male)
Estradiol (male)
Ferritin
Follicle Stimulating Hormone (FSH)
Handgrip strength- average
Handgrip strength- weakest hand
IGF BP3
IGF-1 (Growth Hormone)
Immunoglobulin IgA
Luteinizing Hormone (LH)
Maximum oxygen uptake (female)
Melatonin (6-sulphate)
Noradrenaline- plasma (female)
Noradrenaline- urine
Oral glucose tolerance at 1-hour
Oral glucose tolerance at 2-hours
Thyroid Stimulating Hormone (TSH)
Serotonin (5-HIAA)
Serotonin (5-HT)
Skin-fold thickness- triceps
Skin-fold thickness- back of hand
Smell identification
Static balance
T3 free
T3 total
T4 free
T4 total
Testosterone total
Testosterone binding to SHBG
Waist/ hip ratio

General Health Indicators
From more than 2000 published clinical studies, the Inner-Age medical panel identified 88 general health indicators.

General health indicators are classified as markers that:

Do not result in a clear association with aging.
Have large standard deviations.
May be statistically inaccurate data for biomarker purposes.
Samples may be unrepresentative.
However, whilst they may not be accurate to help capture the biological age of a patient, nonetheless, they are known markers of some diseases and disorders, therefore they deserve to be captured and recorded for future reference.
General health indicators are captured and recorded, as they help to provide information about the patient. With repeat Inner-Age tests, this amassed information can be used to see changes, then as new information comes to light, (through additional published clinical information and the collection of data through the centralized Inner-Age System), these markers may take on a different significance. In other words, Inner-Age will help you to reveal the unseen future health trends, which are usually invisible from the standard perspective.

The general health indicators captured and recorded by the current Inner-Age system are as follows: (Unless indicated general health indicators are for male and female):

17-Hydroxcorticosteroid Total
17-Ketosteriod Total
Acid Phosphatase
Albumin/ Globulin ratio
Alkaline phosphatase
Amylase
Androstanediol Glucuronide
Apolipoprotein A1
Apolipoprotein A1/ Apolipoprotein B ratio
Basophils %
Bilrubin indirect
Bilrubin direct
Bilbrubin total
Blood pressure- diastolic
Blood Urea Nitrogen (BUN)/ creatinine ratio
Calcium
Carbon dioxide
Carcino Embryonic Antogin (CEA)
Ceruloplasmin
Chloride
Cholesterol- HDL
Cholesterol- LDL/ HDL ratio
Chronological age
Coenzyme Q10
Copper (female)
Cortisol
CRR
Creatinine
Eosinophils %
Estriol free
Estrone
Folic acid (folate)
Fructosamine
GGTP
Globulin
Glucose
Glutathione- reduced
Glutathione- measured
Hair baldness (female)
Height
Heratocrit
Hemoglobin level
Hip measurement
Homocysteine
Insulin
Iron
Lactate
LDH (Lactate dyhydrogense)
Lipase
Lipoprotein (a)
Lymphocytes %
MCH
MCHC
MCV
Monocytes %
Neutrophils %
Oxalate
Phosphate (inorganic phosphorus)
Phospholipids total
Platelet count
Potassium
Pregnanediol
Pregnanetriol
Progesterone
Prolactin
Protein total
Pulse rate before exercise (step test)
Pulse rate after exercise (step test)
PSA % free (free PSA index)
PSA free
PSA total (female)
Red blood cell count (erythrocytes)
RDW
Selenium
SGOT (AST)
SGPT (ALT)
Sex hormone binding globulin (SHBG)
Sodium
Testosterone free (female)
Total iron binding capacity
Triglycerides
Unsaturated iron binding capacity
Uric acid
Vitamin B12
Waist/ Hip ratio
WBC
Weight

For more information please contact HB Health

The Inner-Age System
This area reviews the procedure behind Inner-Age.

Inner-Age is the first system in the world that combines numerous physical tests, along with a comprehensive blood and urine evaluation to determine a patient's biological age. The biological age can be viewed as a series of parameters, which are individually weighted to produce a total overall biological age for the patient.

Ultimately, any course of treatment that consists of exercise, lifestyle, diet, drugs, hormones or nutrition can now be monitored, to see how they change individual and total biological age.

All of these 150 tests are outlined below in five categories. First there are the laboratory tests, which highlight the specific tests undertaken in blood and urine, then there are the physical tests that are undertaken in the clinic. Then you can see some of the types of visualizations that are created once all the data has been entered into the Inner-Age system. You can then also learn about how Inner-Age is able to offer individual advice and guidance about how to alter individual biomarkers, and finally there is information about the support systems that are offered by Inner-Age to the clinic. We recommend that you check them out in the order they are listed below.

Laboratory Tests
This area lists all of the tests that are conducted from a blood and urine collection in the current Inner-Age system.

The Inner-Age system uses a 24-hour urine collection and blood draw from a patient to record, collate and evaluate numerous biomarkers.

From the beginning, the Inner-Age medical panel realized that as many blood/ urine markers were needed as was physically possible. It was also recognized that these markers would be dependant upon convenience, (i.e. a lumbar punch to ascertain brain chemical makeup would be out of the question for the majority of people), and cost.

The following list outlines all the 105 blood and urine results that are currently captured, recorded and evaluated by the Inner-Age system.

17-Hydroxycorticosteroid Total
17-Ketosteroid Total
Acid Phosphatase
Albumin
Alkaline Phosphatase
Amylase
Androstanediol Glucuronide
Androstenedione
Apolipoprotein A-1
Apolipoprotein B
Ascorbic Acid
Basophils %
BGP - Bone gla Protein (OsteoCalcin)
Bilirubin Total
Bilirubin Direct
BUN - Blood Urea Nitrogen
Calcium
CEA - Carcino Embryonic Antogin
Carbon Dioxide
Ceruloplasmin
Chloride
Cholesterol - HDL
Cholesterol - Total
Coenzyme Q10
Copper
Cortisol
Creatinine
Creatinine Clearance
CRP-High sensitivity C Reactive Protein
DHEA S
Eosinophils %
Estradiol
Estriol Free
Estrone
Ferritin
Fibrinogen
Folic Acid (Folate)
Fructosamine
FSH - Follicle Stimulating Hormone
GGTP
Globulin
Glucose
Glutathione - reduced
Glutathione - measured
Hemoglobin A1C
Hemoglobin Level
Hematocrit
Homocysteine
IGF BP3
IGF-1(Growth Hormone)
Immunoglobulin - IgA
Insulin
Iron
Lactate
LDH - Lactate Dyhydrogense
LH - Luteinizing Hormone
Lipase
Lipoprotein(a)
Lymphocytes %
MCH
MCHC
MCV
Melatonin (6-Sulphate)
Monocytes %
Neutrophils %
Noradrenaline - plasma
Noradrenaline - urine
Oral Glucose Tolerance Test after 1 hour
Oral Glucose Tolerance Test after 2 hours
Oxalate
Phosphate (Inorganic Phosphorus)
Phospholipids total
Platelet Count
Potassium
Pregnanediol
Pregnanetriol
Progesterone
Prolactin
Protein Total
PSA Free
PSA Total
RBC - Red Blood Count (Erythrocytes)
RDW
Selenium
Serotonin (5-HT)
Serotonin (5-HIAA)
SGOT (AST)
SGPT (ALT)
SHBG - Sex Hormone Binding Globulin
Sodium
T3 Free
T3 Total
T4 Free
T4 Total
Testosterone Binding to SHBG
Testosterone Free
Testosterone Total
TIBC - Total Iron Binding Capacity
Triglycerides
TSH- Thyroid Stimulating Hormone
UIBC - Unsaturated Iron Binding Capacity
Uric Acid
Vitamin B12
WBC
Zinc

Physical Tests
This area lists all of the tests that are derived from the physical measurements in the current Inner-Age system.

Blood pressure- systolic
Blood pressure- diastolic
Blood pulse
Hair baldness
Hair grayness
Arcus Senilis
Height
Waist measurement
Hip measurement
Waist to hip ratio
Weight
Body mass index
Static balance test
Hand grip strength- weakest hand
Hand grip strength- strongest hand
Hand grip strength- average
Basal metabolic rate
Skin elasticity
Skin fold thickness- back of hand
Skin fold thickness- triceps
Near vision
FEV-1 (forced expired volume)
FVC (forced vital capacity)
Body flexibility- anti-flexion
Body flexibility- retro-flexion
Body flexibility- side-flexion left
Body flexibility- side-flexion right
Maximal oxygen uptake
Pulse after exercise
Smell identification test
All these tests are able to be completed using the equipment that is supplied with the Inner-Age system. Specifically, the equipment supplied is:

Digital wrist blood monitor
Spirometer
Dynamometer
Inclinometer
Calipers
Step
Scales
Thermometer
Metronome
Measuring tape
Height roller tape
Stop watch
Krimsky-Prince rule
Smell test answer keys
Inner-Age travel case

Visualizations
This area is about the unique visualizations that are created using the Inner-Age system.

One of the most powerful features of Inner-Age are the easy to understand visual color maps, that form the diagnostic visualizations.

Once all the data has been entered into the Inner-Age system, two kinds of visualization can be created. The first kind is the body map.

Here in the body map on figure 1, the easy to understand colors quickly identify the areas of the body that are aging faster than other areas, and therefore immediately highlights to the physician and the patient, the areas that need the most attention etc.


Figure 1.

The colors are based on the corresponding biological to chronological age of the patient. So, for example, in the body map shown, the patient's red areas indicate the biomarkers that are in excess of 10-years, the orange areas indicating biomarkers that are 5-10 years in excess of chronological age, the yellow areas indicating biological age similar/ close to chronological age, and finally green areas, down to the darkest green which indicates a biological age more than 10-years less than chronological age.

All these colors are explained on the legend that appears in the lower left hand corner of the visualization screen.

At the same time, individual biomarkers can be reviewed simply by pointing the mouse cursor over the area of interest. As shown in figure 2 the precise measurements, including the normal upper and lower parameters for the patient's chronological age, and the individual biological age for that one biomarker are shown in figure 2.


Figure 2.

This same data can also be viewed in the topological map version, as shown in figure 3.


Figure 3.

In this form, a more precise grouping of biological systems can be reviewed for biological age, and once again by simply moving the mouse cursor over the biomarker of interest, reveals the precise measurement, upper and lower parameters for the patient's chronological age, and the individual biological age for that one biomarker, (see figure 4).


Figure 4.

Once a visualization is generated it is always available to be viewed on screen at anytime (for no additional charge). Furthermore, the report can be printed and given to the patient for their own particular copy.

Therefore, with repeat tests it is possible for the first time to scientifically track the progress of an anti-aging/ preventative medicine protocol. These color maps can be compared side by side, and within seconds it can be seen which areas have changed color since the last visit, hopefully all towards green or yellow rather than orange or red! (Thereby indicating that aging is slowing or reversing).

 

Advice and Guidance
This area is about the anti-aging/ preventative medicine advice and guidance that is offered by the Inner-Age system.

Once a VISUALIZATION has been created, the concentration of any proactive action will concentrate on the orange and red areas of the mapping. In other words, the anti-aging medicine will be directed at those biomarkers that are above the chronological age of the patient.

To this end, under the guidance of the Inner-Age scientific panel (see FAQs for details), Inner-Age has created an area that can assist the physician in making decisions regarding potential anti-aging/ preventative medicine.

The goal of the Inner-Age advice and guidance is to provide information that can alter an individual biomarker, normally in either an upward or a downward direction. As such, the criteria used to evaluate potential anti-aging medicines is as follows:

The evidence of its action is based on international published clinical evidence.
It has a proven safety record.
It is known to be efficacious.
It has been in use by anti-aging/ preventative/ alternative medical health practitioners for a reasonable period of time.
That enough information is available about it to indicate potential adverse side effects and contraindications, as well as its beneficial aspects.
That the substance in question can actually alter one or more of the biomarkers in the Inner-Age system.
Inner-Age has detailed 114 such substances into the Inner-Age Anti-Aging PDR (Physician's Desk Reference). The format will be familiar with those who use a standard PDR as it is the same. The Inner-Age advice and guidance then groups all substances into one of 5 categories:

Drug, (meaning a substance that is not found in nature).
Hormone, (meaning a substance that is manufactured within the body).
Nutrition, (meaning any natural substance that can be found in the diet which includes amino acids, vitamins, minerals and herbs etc.)
Lifestyle, (meaning diet, exercise and other environmental factors such as water consumption and exposure to sunshine etc.)
Miscellaneous, (meaning anything that can't be included easily in any of one of the above categories).
The categories have been chosen strictly by those criteria listed above. Because the Inner-Age System is international, we have not tried to group them by legal/ regulatory requirements, i.e. as prescription, controlled or over-the-counter items etc. This was decided because it is too complex to decipher the different regulatory categories for the whole world. For example, the adrenal hormone; DHEA is currently an over-the-counter substance in the USA, but it is a prescription item in most countries, and in some countries, such as the UK, Canada or Australia, it is a controlled substance!

We would like to stress that in all instances trade names were avoided in the Inner-Age advice and guidance section, and that chemical names were used wherever possible. Plus, in all cases the references of the clinical published results, (from which the report was written) are shown at the end of the entry. These parameters help to establish Inner-Age as an independent and scientific system, not bound to any commercial constraints. Furthermore, the clinic is free to incorporate any, all or their own products and protocols into the system. If you would like to see an example of one of the entries of the Inner-Age Anti-Aging PDR, please click here.

As can be seen in figure 1, the screen shot from the advice and guidance section allows the physician to choose any of the suggested products and protocols for the biomarker in question. At present, the suggested products/ protocols are in order of potency to treat the specific biomarker in question.

The physician is then at liberty to recommend dosages and frequency, and write additional notes of advice, and finally printing off an advice and guidance report for the patient to take home with them.

Inner-Age also allows the physician to go back to the patient's details at anytime and see what advice and guidance was offered for each visit etc. Additional visits to existing patient data is free of charge.

The current Inner-Age Anti-Aging PDR contains detailed information about all of the following items:

5HTP
Acarbose
Acetyl-L-Carnitine
Adrafinil
Aminexil
Aminoguanidine
Anastrozole
Androstenediol
Androstenedione
Arginine
Ascorbic Acid
Aspirin
ATP (Adenosine Triphosphate)
Beta Alistine
Bromocriptine
Calcitonin
Calcium
Carnosine
Centrophenoxine
Chaste Berry (Vitex Agnus Castus)
Cholecalciferol
Chondroitin Sulfate
Chromium
Corticotrophin
Copper
CoQ10
Cortisone (Hydrocortisone)
Cyanocobalamin
Cytomel (Thyroid)
Deprenyl
DHEA
DIM (Di-indolylmethane)
Erythropoietin
Estradiol (Estrogen)
Estriol (Estrogen)
Estrogen
Estrone (Estrogen)
Finasteride
Folic Acid
Garlic
Gerovital-H3
Ginkgo Biloba
Glucosamine
Glycoprotein
Human Growth Hormone
Hydergine
Hydrocortisone
I3C (Indole-3-Carbinol)
Idebenone
Iodine
Ipriflavone
Iron
L-Carnosine (Carnosine)
L-Thyroxine (Thyroid)
L-Tryptophan
Lycopene
Magnesium
Melatonin
Metformin
Mild Silver Protein
Milk Thistle
Minoxidil
Modafinil
Molybdenum
MSM
N-acetylcarnosine (Carnosine)
N-acetylcysteine
Nandrolone
Niacin
Ornithine
PABA
Phenytoin
Phosphatidylserine
Phytonadione
Picamilone
Piracetam
Policosanol
Potassium
Pregnenolone
Progesterone
Propranolol
Pyridoxine
Red Yeast Rice Extract
Resveratrol
SAMe
Saw Palmetto
Selenium
St. John's Wort
Testosterone
Thiamine
Thymus
Thyroid
Thyroid T3 (Thyroid)
Thyroid T4 (Thyroid)
TMG
Tocopherol
Tretinoin
Tribulus Terrestris
Turmeric
Urtica Dioica
Vinpocetine
Vitamin B1(Thiamine)
Vitamin B12 (Cyanocobalamin)
Vitamin B3 (Niacin)
Vitamin B6 (Pyridoxine)
Vitamin C (Ascorbic Acid)
Vitamin D (Cholecalciferol)
Vitamin E (Tocopherol)
Vitamin K (Phytonadione)
Vitex Agnus Castus
Whey Protein
Xylitol
Yohimbine
Zinc
Further updates are planned to the Inner-Age advice and guidance, including an on-line Anti-Aging PDR, and as the area of recognizing anti-aging treatments is expanding so rapidly, it is an area that Inner-Age is keen to stay abreast of.

Eventually, we believe that you will come to regularly access the detailed international information, that is being gathered within the Inner-Age advice and guidance section. Inner-Age is making it much easier for you to know about the latest anti-aging treatments.

Support
This area describes the various support programs that are available from Inner-Age.

Inner-Age is aware that today, it is not enough just to have the best piece of diagnostic equipment for biological age on the market. Therefore, we are supporting anti-aging clinics who are members of the Inner-Age program in the following ways:

A 24/ 7 e-mail help desk for software support, so that any connectivity or system problems, or whilst you are in the Inner-Age System, can be addressed as soon as possible.
A "Clinical Protocol" book that tells you the exact order in which to run the PHYSICAL TESTS, so that you can maximize the efficiency of your time within the clinic and ensure that high standards are met, but that time is not wasted.
Inner-Age provides you with all the equipment you need to capture physiological data. This equipment remains the property of Inner-Age, but whilst you remain an active Inner-Age member, the equipment will be replaced free-of-charge if it is accidentally broken, damaged or becomes worn-out.
An "Anti-Aging Medicine PDR" that is updated as the ADVICE AND GUIDANCE is updated. This valuable tool helps you to stay ahead of the latest thinking in the treatment of patients with anti-aging medicine.
Heavily discounted complete panel of blood and urine LABORATORY TESTS, all designed specifically for the Inner-Age system, all conducted through an approved Inner-Age laboratory.
An on-line private forum/ chat group for Inner-Age members through the Inner-Age web site. A place where medical health professionals interested in anti-aging/ preventative medicine can swap ideas and communicate with one another.
Free and continuous updates to both the biomarker/ VISUALIZATION software and the advice and guidance. Once updates take place you will be informed via e-mail of the relevant changes. This way each time you log onto the Inner-Age system you are taking advantage of the latest published clinical results, and yet all updates are included in the yearly membership fee, (see COSTS).
We are also working so that you can pay for additional training sessions with anti-aging medical professionals. In other words, you can have the possibility for an anti-aging expert to come to your clinic to train you and your staff in various aspects of anti-aging medicine. Thus completing the circle with the Inner-Age System, the reason why certain measures are captured and then what they mean. Some further details can be seen under FAQs.
Plus, we can also make available marketing materials, to help your clinic market Inner-Age to your patients. Marketing materials will include such items as: leaflets, posters, adverts and a short-looped DVD designed for a waiting room.

A complete Inner-Age evaluation takes 2-hours, of which the 2nd hour is the wait for the 2nd glucose tolerance test. Hence, this time can be taken by the clinic to avail the patient of the services of the clinic, either to give them massage, facials etc., or to educate them about anti-aging medicine. Any additional time required is at the discretion of the physician and the patient, both in the initial consultation and the diagnosis of the Inner-Age results, i.e. to decide what course of preventative treatment is required etc.

For more information please contact HB Health

Testimonials
Read about what professional people and patients have to say about the Inner-Age system here!

Ward Dean, M.D.
Author, Biological Aging Measurement.
Author, Neuroendocrine Theory of Aging.
Author, Smart Drugs and Nutrients,
R&D Director, Vitamin Research Products.

"Inner-Age is a major advancement, representing the arrival of the first comprehensive package for the diagnosis of aging. It is an invaluable tool for any physician who wants a total solution to practice anti-aging medicine."

Garry Gordon, M.D.
President, International College of Advanced Longevity.
President, Gordon Research Institute.
Founder, American College for Advanced Medicine.

"The realization of Inner-Age is a giant leap forward in the establishment of anti-aging medicine as a clinical science. I believe that this system will become the foundation of anti-aging clinics everywhere."

Marios Kyriazis, M.D.
President, British Longevity Society.
Author, Anti-Aging Plan.
Author, Look Young Bible.

"Inner-Age is one of the most important, innovative and significant advances made in recent years for the ongoing development of anti-aging medicine."

Comments from Inner-Age Patients
"I took the Inner-Age diagnostic test and my results revealed irregular levels of PSA, which is an indicator of prostate cancer. Upon further tests I discovered that I had developed the cancer, even though I had always maintained a healthy and active life and had suffered from no symptoms. Fortunately, due to the Inner-Age test, I was able to detect and treat the disease early. If I had not taken the Inner-Age test when I did, the disease may have remained undetected until it had reached a more advanced state, which could have proved significantly more difficult to treat."

More patient comments to follow soon....

For more information please contact HB Health

FAQs
This area reviews some of the most frequently asked questions about Inner-Age.

What is the aim of Inner-Age?

Inner-Age is designed to give an accurate and comprehensive picture of the patient's biological age, as well as ascertaining their Aging-Rate™, in other words, you can determine if the patient is aging quickly or slowly.
Inner-Age is also able to highlight individual aging trouble spots, so that a preventative focus can be given in an anti-aging regime.
Inner-Age is also able to record so many measurements that the system itself can be evaluated and kept up-to-date. In other words, Inner-Age members are permanently at the forefront of anti-aging medicine progress.
Inner-Age can ascertain whether individual treatments or protocols are working, and therefore if they are helping to slow down and reverse the aging of a patient. No matter what practices your clinic is adopting, whether they be hormone replacement therapy, acupuncture, reflexology or nutrition etc., Inner-Age shows you quickly and easily how an individual program performs.
Inner-Age is the ultimate diagnostic system for preventative medicine. At last you can prove to your patients that you are reversing and controlling their aging, helping to prevent serious diseases and disorders from coming to light in the years to come. Patients become very loyal when they can see for themselves that your protocols and products work.
You can see an outline of the Inner-Age System at the OVERVIEW.

How many test inputs can Inner-Age currently handle?

Inner-Age is currently capable of inputting over 150 measurements, these are made up of physical measurements, as well as measurements from blood and urine. For further details see CONCEPT and SYSTEM.

Do you need to do all the measurements to use Inner-Age?

No, it is not necessary to undertake all the tests. The most vital measurements are the BIOMARKERS, however we strongly recommend that both the CANDIDATE BIOMARKERS and GENERAL HEALTH INDICATORS are also entered. Why? Because the more measurements that are included, the more accurate the overall biological age becomes. Furthermore, we are talking about preventative medicine. How can you know what to prevent in the future, if measurements are not recorded today? Therefore it makes sense that as many measurements as possible are recorded, all of course within the constraints of convenience and cost.

What is the difference between a biomarker, candidate biomarker and general health indicator?

That question is answered in the same relevant sections of BIOMARKERS, CANDIDATE BIOMARKERS and GENERAL HEALTH INDICATORS.

How were the actual scientific parameters used in Inner-Age decided upon?

The initial basis of the research was ascertained from Dr. Ward Dean's book- Biological Aging Measurement. But as that book was published in 1988, the Inner-Age scientific panel also looked at further published clinical research, referring to biomarkers since 1988. In all, it is estimated that over 2000 published clinical studies have been evaluated, referring to more than 500,000 patient data.

How were the individual categories weighted for their importance?

The scientific panel of Inner-Age decided what was most important and what was most accurate. As the decision regarding the three categories of measurements was already made (see the question above), the matter now revolved around the need to decide what was more important than something else etc. Essentially, the panel decided that if a measurement had a more significant medical purpose it had a higher category, for example hair baldness may be a reasonable enough biomarker of aging, however no-one died of being bald! So naturally it is weighted with a low significance, but blood pressure may indicate a more serious condition, therefore it is weighted higher.

How can I get precise details about the "workings" of Inner-Age?

At present the information is being kept proprietary, particularly as patents are pending. However, at a later date more information about the "workings" behind Inner-Age will be made available, so that the mass of science behind it can be more clearly seen.

Who is the Inner-Age scientific panel and how much work went into the development of Inner-Age?

The scientific panel is headed by its Medical Director and the world famous Geriatrician, Dr. Ward Dean:

Ward Dean, M.D., Dr. Dean is the coauthor with Vladimir Dilman, M.D., of the Neuroendocrine Theory of Aging, as well as the author of the magnum opus- Biological Aging Measurement, and numerous other health anti-aging publications- including the Smart Drug series of books. Dr. Dean is also the R&D Director of Vitamin Research Products in Nevada. Details of Dr. Dean can be seen at www.warddeanmd.com Dr. Dean has therefore bought his extensive skills, knowledge and contacts to Inner-Age to oversee the scientific development and weighting of the system.

International Antiaging Systems, (IAS); have been involved in anti-aging medicine for more than 12-years and are regarded as one of the most innovative organizations in the world today, maintaining their approach to cutting-edge preventative medicine. Thus, IAS have been able to advise Inner Age on the trends and focuses of the industry, as well as draw down on their considerable reputation and contacts within the field. IAS have realized that Inner Age represents a breakthrough in biological aging measurement, and that it brings to the marketplace for the first time, the proof that anti-aging medicine is scientific, and that when applied properly can be proven to work.

Furthermore, Inner-Age has been supported over the last years by a development staff of nearly 30, including statisticians and various software designers etc. Inner-Age is a very significant investment in the diagnosis of aging having cost many millions of Dollars to bring into the marketplace.

Is Inner-Age a complete system for an anti-aging center?

Inner-Age is an extremely valuable tool, and certainly helps to streamline the clinical operation by evaluating patients in approximately 2-hours total time. However, the SYSTEM itself is designed to be flexible. Unlike other systems, there is no tie-in, no compulsory use of products etc., so that ultimately the results obtained from Inner-Age can then be used by anti-aging physicians as part of their own individual packages, and also for the particular requirements of the patient in question.

The ultimate anti-aging medicine is very individual, Inner-Age allows this to be the case, as each physician and each patient will have their own ideas about what should be applied in the way of treatment. Whilst Inner-Age provides some ADVICE AND GUIDANCE the clinic is free to apply whatever further tests and protocols etc., that it sees fit. To see all the possibilities of Inner-Age go to ADVANTAGES.

Therefore whilst Inner-Age can be used as a complete system, (a system that caters for all the proven markers of aging and records 150 plus markers), it can also be used as part of an even bigger package. Inner-Age is therefore able to be as big or as small as your clinical requirements need.

When will Inner-Age be updated?

One of the great advantages of Inner-Age over any other system is its ability to collect data on a global basis. Therefore, this data can be evaluated and new relationships (and indeed new biomarkers), can be identified. Accordingly, each time members log into the system, they are benefiting from the latest information and updates. What is more, this support is provided free of charge to members of the system. In this regard, Inner-Age is constantly updating the data.

It is envisaged that the current system represents a gold standard level. So, with regard to future additional tests etc., there will be upgradeable versions to Platinum/ Diamond level, (that will require further tests, at additional cost of course), and will allow other interesting data to be collected, recorded and possibly even evaluated. There may also be a cut-down version (perhaps a Bronze or Silver level), which could give a rough indication of condition for a smaller fee. The Inner-Age system is flexible, but at the same time it is scientific and designed to give accurate and useful data about a patient's aging condition and rate.

How was the advice and guidance organized?

Advice and guidance is based on the ability for a given substance or protocol to alter an individual biomarker, either in an upward or downward direction. As the unique VISUALIZATION reports of Inner-Age indicate if the patient is over, under or about the same as their chronological age, you can then act on that information. The decision can then be made whether to increase, or lower an individual marker (i.e. LDL and HDL cholesterol). The advice and guidance then offered, comes in five parts:

Lifestyle: This currently includes anabolic, aerobic and flexing exercise, diet (low carbohydrate, low fat, high protein and reduced calorie), drinking water and exposure to sunshine.
Nutrition: This section is described as natural substances that can be found in the diet, i.e. vitamins, minerals and amino acids etc.
Hormones: This section is described as chemicals made by the body, i.e. DHEA, Human Growth Hormone and Melatonin etc.
Drugs: This section covers international medicines, but the accent is on preventative medicines and alternative uses etc.
Miscellaneous: This section covers anything not able to be defined by the above.
Advice and guidance can be chosen by individual category, or in an order of potency, (first listed being the most potent). This order has been defined by the Inner-Age scientific panel. We have not listed any trade names, and in each case we have listed the clinical references, so that the proven uses for any products in question can be checked for yourself. The Inner-Age System is currently able to define approximately 120 different anti-aging products and protocols. For further details see ADVICE AND GUIDANCE

Does Inner-Age provide specific training about Anti-Aging Medicine?

The whole of the medical community wants an easy answer to anti-aging medicine, but unfortunately there isn't one. As there is no recognized single body for anti-aging medicine, (it is not like main stream medicine where there are clear diplomas and training/ advice from approved medical bodies etc.) So at present, the physician interested in anti-aging medicine has to join as many organizations as possible, in order to learn as much about the field as possible. Organizations such as the American Academy of Anti-Aging Medicine (A4M), International Antiaging Systems (IAS) or the Life Extension Foundation (LEF) etc.

Furthermore, the physician also needs to attend the major conferences for lectures and networking opportunities, events such as the A4M conferences, or the Monte Carlo/ International Anti-Aging Conference etc.

What Inner-Age is organizing, is to work with a number of renowned anti-aging physicians that could be available at extra cost, (plus expenses), to travel to your facilities and spend 1-2 days with your team, covering the aspects of anti-aging medicine that you are most interested in applying. We expect to shortly have a questionnaire offering different training programs, each one timed, and with a minimum requirement of 4-hours etc. (This could vary on the time it takes for the training physician to travel to you).

Sessions would include programs such as the following:

Basics: Including terminology, theories of aging, oxidation, antioxidants. UV radiation. Glycosylation, advanced glycosylation end (AGE) products, cross-linking. Examples of AGE inhibitors and cross link-breakers, genes, telomeres, cancer and aging. DNA damage, acetylation and methylation, longevity genes, nutrition and nutritional supplements. Caloric restriction and other attempts at extending life span, lifestyle and aging.
Intermediate: Including a summary of the above, plus heat shock proteins. Post-translational modification/ abnormal proteins, proteolysis. Apoptosis in aging and cancer. Cellular aging, membrane receptors. Mitochondria. Biological aging of the eye, skin, muscle/ heart, vascular system, bone and other tissues. Immune system, auto-immunity. Age-related modifications to the immune system. Consequences. Evaluating immune system status. Hormonal ageing. Basics of the menopause, and other hormone-dependant processes such as hypothyroidism and diabetes. Discussion of melatonin, thyroxin, testosterone, human growth hormone, DHEA and other hormones. The science behind the biomarkers of aging. Examples of biomarkers and analysis of scientific evidence. Scientific validation of the physical examination equipment used with Inner Age (dynamometer, skin-fold measurement, inclinometer, Spirometer etc.)
Advanced: Including a summary of all of the above, plus: Chronic Inflammation. Biological basis of age-related illness (Alzheimer's disease, Parkinson's disease, other neuro-degenerative diseases. Other chronic inflammatory diseases (e.g. arthritis). The aging brain. Neurodegeneration and neuroprotective agents. Memory and cognition. Aging of the rest of the nervous system (e.g. senses, balance). Psycho-neuroimmunology and its relevance to aging. The future. Stem cells, cloning, nanotechnology. Dynamical systems and reliability theories. Hormesis. Theoretical models for healthy aging and life prolongation. In-depth discussion of organ aging, hormones, specific anti-aging drugs and supplements. Strategies for holistic, effective and long-term therapies.
There would also be specific sessions aimed at particular biomarkers and treatment protocols, for example human growth hormone.

For more information please contact HB Health

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